Restylane Family Costs: Kysse, Lyft, and Defyne Pricing Guide

A clinician in a modern aesthetic clinic shows a patient a price sheet while Restylane syringes labeled Kysse Lyft Defyne sit on a tray, conveying consultation and pricing transparency.

Restylane Kysse, Lyft, and Defyne are popular hyaluronic acid fillers with different uses and pricing. This guide breaks down typical US price ranges, explains how clinics set fees for fillers and other non-surgical procedures like Botox and CoolSculpting, and gives practical steps to compare offers so you get safe, cost-effective treatment without surprises.

Understanding the Restylane Family and Typical Uses

The Restylane family of dermal fillers, manufactured by Galderma, is built on hyaluronic acid (HA), but each product is engineered differently to solve specific aging concerns. Understanding these differences is crucial because the specialized formulation directly dictates where the product is used, how many syringes you need, and ultimately, the price per syringe.

These specialized fillers are not interchangeable. They vary based on factors like gel firmness, particle size, and cross-linking density. These technical details determine the product’s G-prime, which is the measure of the gel’s ability to lift and maintain shape. A higher G-prime means a firmer gel, suitable for deep structural support. A lower G-prime means a softer, more flexible gel, suitable for dynamic areas.

It is important to note that the Restylane family often carries a higher price tag than basic or generic hyaluronic acid fillers. This premium is due to the proprietary technology inside the gel. Products like Restylane Defyne and Kysse use XpresHAn technology, which allows the filler to move naturally with your face when you smile or talk, preventing a stiff or frozen look. Generic or older fillers might be cheaper to manufacture, but they may not last as long or provide the same natural tissue integration. When you pay for Kysse or Lyft, you are paying for a product that has undergone extensive FDA testing for safety and offers a specific texture matched to the treatment area.

Restylane Kysse is specifically designed for lip enhancement. It uses Galderma’s XpresHAn Technology to create a gel that integrates smoothly into the delicate lip tissue. This allows for natural movement and flexibility, which is essential when talking, smiling, or kissing. The goal of Kysse is not just volume, but improved texture and definition without a stiff or unnatural feel. Because Kysse is optimized for this dynamic environment, its formulation is softer and more pliable than the fillers used for deep structural support. Typical treatment involves one syringe, which is usually enough to add volume and define the borders of the lips. However, patients seeking significant volume increases or correction of asymmetry may require 1.5 to 2 syringes initially. Kysse results often last up to one year, sometimes longer, but lips are a high-movement area, so touch-ups are common around the 9 to 12-month mark.

Restylane Lyft is the workhorse of the family when it comes to volume and lift. It has a significantly higher G-prime, making it ideal for areas needing structural support, like the midface. Its primary clinical uses are cheek augmentation and correcting age-related volume loss in the midface. Lyft is also FDA-approved for use in the hands to restore volume loss there. Since Lyft is designed to lift and project, it requires a firmer, larger particle size formulation compared to Kysse. This structural capability often places Lyft at a higher price point per syringe due to its specialized lifting capacity. For cheek augmentation, a realistic treatment plan often requires 1 to 2 syringes per side, meaning a total of 2 to 4 syringes for a full correction, depending on the degree of volume loss. Results from Lyft in the cheeks are generally long-lasting, often extending to 12 to 18 months before maintenance is needed.

Restylane Defyne is engineered to treat deep facial wrinkles and folds, such as severe nasolabial folds (smile lines) and marionette lines. Like Kysse, Defyne utilizes XpresHAn Technology, but its cross-linking is designed for deeper injection and greater longevity while still allowing for natural facial expressions. Defyne is firmer than Refyne but softer than Lyft. This balance makes it excellent for smoothing deep creases without immobilizing the surrounding tissue. It is also frequently used off-label for subtle jawline contouring. The specific formulation needed for deep correction means Defyne often carries a mid-to-high price tag within the Restylane line. Treating deep nasolabial folds typically requires 1 to 2 syringes total, depending on the severity of the lines. If the jawline is also contoured, an additional 1 to 2 syringes may be necessary. Defyne results are expected to last around 12 months or slightly longer.

The technical characteristics of these fillers directly influence their cost and the injector’s technique. Products with more complex cross-linking or specialized particle sizes, like Lyft and Defyne, often require more sophisticated manufacturing processes, which drives up the wholesale cost. Clinics then pass this specialized cost onto the consumer. When you see a higher price for Lyft compared to a standard Restylane product, you are paying for that increased lifting capacity and longevity.

When budgeting for treatment, you must move beyond the per-syringe price and consider the total number of syringes required for a realistic outcome. A lip enhancement with Kysse is often a single-syringe treatment, costing approximately $600 to $950 total. However, a full midface lift using Lyft might require 3 syringes, pushing the initial investment to $2,100 to $3,600 or more. Treating deep nasolabial folds with Defyne might require 2 syringes, placing the cost around $1,200 to $2,000. These are initial correction costs.

Since HA fillers are temporary, you must also factor in maintenance. If your Lyft results last 15 to 18 months, you need to budget for a touch-up every year or so. These maintenance treatments usually require fewer syringes than the initial correction—perhaps just one syringe of Lyft to refresh the volume—but they are a necessary part of the long-term cost projection for aesthetic procedures. Always ask your provider for a realistic treatment plan that includes the number of syringes needed for the initial correction and the expected maintenance schedule. A filler that costs $100 more per syringe but lasts six months longer can actually be the more economical choice over a five-year period.

US Pricing Breakdown and Realistic Cost Ranges

The cost of a single syringe of Restylane Kysse typically falls between $600 and $950 in the current 2025 market. This range exists because different clinics have different overhead costs. A high-end plastic surgery center in a major city will charge more than a high-volume medical spa in the suburbs. You might find promotional prices as low as $550 during seasonal sales. Some premium boutiques in areas like Beverly Hills or Manhattan might charge over $1,000 for the same product. The price often reflects the skill of the person holding the needle. A board-certified dermatologist with years of experience will naturally cost more than a newer injector at a chain clinic.

National Price Ranges for Restylane Products

The pricing for the Restylane family varies based on the specific technology used in the gel. Restylane Lyft usually costs between $700 and $1,200 per syringe. This product is thicker and designed for deep structural support in the cheeks or hands. Because it requires precision to avoid a heavy look, the injector expertise adds to the final bill. Restylane Defyne sits in a similar bracket. You can expect to pay $600 to $1,000 per syringe for Defyne. It uses XpresHAn technology to allow for natural movement in the lower face. These prices are typical full retail ranges. They are not exact quotes because every face requires a different amount of product.

Restylane Product Low End (Promos) Mid Range (Standard) High End (Premium)
Restylane Kysse $550 $750 $950
Restylane Lyft $700 $900 $1,200
Restylane Defyne $600 $800 $1,100

The low end of these ranges usually comes from high-volume clinics that buy in bulk. According to wholesale data, a clinic might pay around $179 for a single syringe of Kysse. If they buy more than twenty units at once, that cost drops to roughly $159. Clinics that pass these savings to you can offer lower retail prices. The mid-range represents the average cost at a reputable medical spa. The high end reflects the premium you pay for a top-tier injector or a luxury location.

Regional Variation and Market Factors

Location plays a massive role in what you pay. In major metropolitan areas, clinics face higher rent. They also pay more for insurance and staff. These costs get passed to the patient. You can expect to pay 20 to 50 percent more in a city center compared to a rural area. For example, according to Celibre Medical, the average price for Restylane in the Los Angeles area is around $550, but it can go much higher depending on the specific product used. Competition also matters. In a city with a medical spa on every corner, you might see more aggressive discounts. In a smaller town with only one provider, prices tend to stay fixed.

Local demand for specific looks can shift prices too. In areas where lip fillers are extremely popular, Kysse might be priced competitively to draw in new clients. In places where cheek fillers are the main request, Lyft might see more frequent promotions. You should always check the local market averages before booking. A price that seems too low for a major city might be a red flag for a counterfeit or gray market product. Buying fillers from outside the United States is illegal and dangerous. Stick to providers who use FDA-approved products from official distributors like Galderma.

Bundling and Multi-Syringe Discounts

Many patients need more than one syringe to reach their goals. A full cheek augmentation often requires two to three syringes of Restylane Lyft. Because of this, many clinics offer bundle pricing. You might pay full price for the first syringe and get $50 or $100 off each additional one. Some offices create package deals for specific areas. A liquid facelift package might include four syringes of various Restylane products at a flat discounted rate.

Another common way to save is through neurotoxin combinations. Combining treatments is very common and often referred to as a “liquid facelift.” You can get Dysport or Botox to smooth forehead lines while using Restylane to add volume to your cheeks. This often saves you time and money. Some clinics offer a discount on filler if you also get a certain number of units of Dysport. For example, OU Beauty has offered $100 off a Restylane syringe when paired with 72 units of Dysport. These bundles make sense because the two treatments work together to refresh the face, allowing the injector to balance your entire face at once for a more harmonious result.

Additional Fees to Expect

Do not just look at the syringe price. Many clinics charge a separate consultation fee. This fee usually ranges from $50 to $200. It covers the time the provider spends analyzing your face and creating a custom treatment plan. In most cases, this fee is applied to your treatment if you book it within a certain timeframe. However, if you decide not to move forward, you usually lose that money. Always ask if the fee is a credit toward the procedure before you pay it to prevent surprises.

You should also ask about touch-up policies. Most clinics include a two-week follow-up in the initial price to check your results. If you need a small adjustment two weeks later, some injectors include this for free. Others charge for the extra product used. If you need a tiny bit more filler to fix an asymmetry, some offices charge a small fee for the extra product, while others might charge for a full syringe if they have to open a new one. It is important to get these details in writing before the first injection happens.

Some high-end clinics also bill an injector fee separately from the product cost. This is more common with famous plastic surgeons. You are paying for the product and the hands that deliver it. Follow-up visits are usually included in the initial price, but it is wise to confirm this. If you experience a complication, you want to know if the clinic will cover the cost of the dissolving agent or if that will be an extra expense.

Comparing Non-Surgical Procedure Pricing

It helps to compare filler costs to other popular treatments. Botox and Dysport are priced per unit. In late 2025, you might pay $10 to $20 per unit for Botox. A typical treatment for forehead lines might use 20 to 40 units. This makes the total cost lower than a syringe of filler. However, the results only last three to four months. Filler lasts much longer.

CoolSculpting is another common comparison. It is priced per cycle. One cycle usually costs between $750 and $1,000. Most people need multiple cycles to see a change in body contour. While a syringe of Restylane Defyne might seem expensive at $800, it provides an immediate result that can last up to a year. Understanding these different pricing mechanics helps you plan a long-term beauty budget. You can decide if you want to spend a smaller amount frequently on neurotoxins or a larger amount once a year on fillers.

How Clinics Price Services and How to Avoid Overpaying

The price tag on a syringe of Restylane Kysse or Lyft is not just the cost of the gel itself. When you compare prices between clinics in the USA, you are comparing business models, expertise levels, and geographic locations. Understanding how clinics build their pricing helps you avoid paying too much for the same service.

Understanding the True Cost of a Syringe

Clinics must account for several factors when setting the retail price for non-surgical procedures like dermal fillers. The final price reflects far more than the wholesale cost of the product.

Key Pricing Components

  • Product Cost: The clinic pays a wholesale price for each syringe of Restylane. For example, the bulk wholesale cost for Kysse might be around $160 to $180 per syringe. The retail price must cover this initial investment plus a significant markup to sustain the business.
  • Injector Skill and Experience: This is often the largest variable. A board-certified plastic surgeon or dermatologist with decades of experience commands a higher fee than a newly trained Registered Nurse. You are paying for their deep knowledge of facial anatomy, their artistic eye, and their ability to handle complications safely.
  • Clinic Overhead: High rent in major metropolitan areas like New York or Los Angeles, expensive medical equipment, highly trained support staff, and utilities all contribute to overhead. Clinics in high-cost areas must charge more to keep the doors open.
  • Geographic Demand: In areas with high demand for aesthetic services, prices naturally rise. Clinics in competitive, affluent suburbs often charge premium rates reflecting the local market expectation.
  • Marketing and Promotions: The cost of advertising, maintaining a website, and running social media campaigns is factored into the service price.
  • Liability and Insurance: Medical malpractice insurance for injectable procedures is mandatory and costly. This essential safety net adds to the per-syringe fee.

Pricing Models: Syringe, Area, or Flat Fee

When you get a quote, make sure you know exactly what pricing structure the clinic uses. Transparency here is key to comparison.

  • Pricing Per Syringe: This is the most common and transparent model for Restylane products. You pay a set price for each 1cc syringe used. If you need two syringes of Lyft for your cheeks, you multiply the per-syringe price by two. This model is easiest to compare across different practices.
  • Pricing Per Area: Some clinics quote a fixed price for treating a specific zone, such as “Lip Augmentation” or “Nasolabial Fold Correction.” This price usually includes a predetermined volume, often one or two syringes. Always clarify the exact volume included. If your anatomy requires more product than the standard allowance, the price will increase.
  • Flat Treatment Fees: These are less frequent but sometimes used for comprehensive treatments like a “Liquid Facelift” or full facial balancing. These fees bundle multiple products and areas. Ensure the written quote itemizes the exact number of syringes of Kysse, Lyft, or Defyne included in the flat fee so you can calculate the true value.

Prioritizing Safety: Why Injector Skill Matters Most

It is tempting to choose the lowest price, but dermal fillers are medical procedures with real risks. The cost of correcting a poor result or managing a serious complication far outweighs any initial savings. An inexperienced injector might place the product too superficially or, worse, accidentally inject it into a blood vessel. Correcting bad filler is expensive; you might have to pay for hyaluronidase to dissolve the old product, and then pay again for new filler. It is usually cheaper to pay more for an expert the first time.

You must evaluate injector credentials thoroughly. Look beyond the title. Confirm the injector is a board-certified physician, a Physician Assistant, or a Registered Nurse who specializes in aesthetic medicine and works under direct medical supervision. Ask specifically about their experience with the Restylane family of products. An injector who has performed thousands of injections is better equipped to deliver natural results and manage rare but serious issues like vascular occlusion than someone who just finished a weekend training course. Paying a higher price for proven expertise is an investment in your safety and satisfaction.

If a complication occurs, like a lump or an infection, a good clinic should handle the initial management. However, you should ask about this policy upfront. Serious complications might require visits to a specialist, and those costs are usually not covered by the aesthetic clinic. A transparent clinic will give you a total price that covers the product, the expertise, and the follow-up care. If they are vague about the numbers or complication policies, it is a red flag.

Negotiation and Value Strategies

While you should not haggle over the price of a single syringe, there are smart ways to reduce your overall treatment cost.

  • Multi-Syringe Discounts: If your treatment plan requires multiple syringes, always ask for a volume discount. Clinics often reduce the per-syringe price when you purchase three or more units at once.
  • Package Pricing: Look for bundles that combine different treatments. Many clinics offer a discount when you combine Restylane fillers with a neurotoxin like Dysport.
  • Seasonal Promos vs Membership Programs: Seasonal promotions offer short-term savings. If you plan to receive treatments regularly, a membership program might offer better long-term value. These often involve a monthly fee that translates into a consistent discount on all services.
  • Financing Options: Many patients use medical financing like CareCredit or Alphaeon. This allows you to break a $2,000 treatment into monthly payments. It can be a good tool if the clinic offers a zero-interest period. However, you must be careful with the interest rates. If you do not pay the balance before the promotional period ends, the interest can be very high, sometimes reaching 26 percent or more. Only use financing if you have a clear plan to pay it off quickly.

Your Practical Shopping Checklist

Use this checklist during your consultations to ensure you are comparing quotes accurately and minimizing the risk of hidden fees or substandard care.

  • Compare three quotes: Reach out to at least three different clinics in your area to get a sense of the local market rate. This helps you identify if a price is suspiciously low or unnecessarily high.
  • Request itemized written quotes: The quote must specify the exact product name, such as Restylane Defyne, and the total volume in milliliters or syringes. Ask if the price includes the injection fee or if that is added later.
  • Ask how many syringes they recommend and why: A good injector explains the rationale. For example, they might recommend two syringes of Restylane Lyft for optimal cheek projection.
  • Verify which brand will be used: You have the right to know exactly what is being put into your body. Ask your injector to show you the box. Check for the FDA approval seal and the expiration date. The syringe should be opened in front of you. If the price seems too good to be true, the clinic might be using “gray market” fillers imported from other countries, which are not regulated by the FDA and can be dangerous.
  • Ask about anesthesia and aftercare included: Most Restylane products contain lidocaine, but confirm if topical numbing cream is included in the price. Ask about follow-up visits and any included aftercare products.
  • Check before and after galleries and patient reviews: Look for consistency and quality in their work, especially on patients with similar features to yours.
  • Confirm revision or complication policies: Find out what the clinic does if the results are uneven or if you are unhappy with the outcome. Some clinics offer minor touch-ups at a reduced rate or for free within a certain timeframe. Ask specifically about the cost if you need hyaluronidase to dissolve the filler.

Red Flags You Must Watch Out For

Protect yourself from overpaying or receiving substandard care by recognizing these warning signs.

  • Extremely Low Pricing: If a clinic offers Restylane Kysse for $350 per syringe when the regional average is $600 to $800, this is a major red flag. They may be using illegally imported, non-FDA approved product or severely cutting corners on safety and training.
  • Vague Product Answers: If the clinic staff cannot clearly state the exact Restylane product they use or avoid showing you the product box, assume they are using a cheaper, potentially unsafe alternative.
  • No Consultation: A reputable clinic requires a detailed consultation to review your medical history and assess your facial structure. Skipping this step indicates a lack of professionalism and safety focus.
  • Pressure to Buy Additional Syringes on the Spot: If the injector tries to convince you to add two more syringes of Defyne right before the injection, resist the pressure. A proper treatment plan should be agreed upon during the consultation.

Conclusions and Practical Next Steps

The total price you pay for Restylane treatments depends on several moving parts that can shift the final bill by hundreds of dollars. You have seen that a single syringe of Restylane Kysse might cost $550 at a high-volume clinic in Los Angeles while a boutique office in Florida or New York might charge $950 or more for the same product. These differences are not random. They are driven by the specific type of filler used, the expertise of the person holding the needle, the physical location of the clinic, and the complexity of your specific facial anatomy. Fillers like Restylane Lyft are designed with a firmer gel to provide structure in the cheeks or hands, which often requires a different injection technique than the softer, more flexible Restylane Kysse used for lip enhancement. Restylane Defyne uses specific technology to allow for natural movement in deep folds, and this specialized engineering is reflected in the retail price. When you see a wide range of quotes, remember that you are paying for the product as well as the clinical environment and the injector’s years of training.

To ensure you get the best value without compromising your safety, you should follow the specific steps outlined in the checklist above before you commit to a procedure. This process helps you avoid the common trap of choosing a clinic based solely on a low price tag, which can sometimes lead to poor results or the use of non-FDA approved products. Taking the time to do your homework will give you the confidence to book your appointment knowing you have vetted the provider and the costs involved.

Balancing the cost of these procedures with the quality of the results is the most important part of your decision. It is often tempting to go with the cheapest option, but in the world of aesthetic medicine, a lower price can sometimes indicate a lack of experience or the use of products purchased through unofficial channels. Clinics that offer prices significantly below the wholesale cost of the product are a major red flag. For instance, the wholesale price for Restylane Kysse is around $179 per syringe for small orders, so a retail price that sits too close to that number suggests the clinic might be cutting corners on safety, insurance, or staff training. You should prioritize injectors who are transparent about their pricing and have a proven track record of natural-looking results. An experienced provider might charge more upfront, but their ability to place the filler correctly can mean you need fewer syringes or fewer touch-ups in the long run.

The geographic location of the clinic will always play a role in what you see on the bill. In major metropolitan areas, the overhead for running a high-end medical spa is substantial. You can find more details on how these factors influence the Restylane cost across different regions to help you set a realistic budget. If you are looking for cheek augmentation, keep in mind that the Restylane Lyft cheeks cost often involves multiple syringes to achieve the desired lift, so a lower price per syringe might be offset by the volume of product required. Always ask your injector for a realistic estimate of how many syringes you will need during your initial consultation.

Your goal should be to find a middle ground where the price is fair and the provider is someone you trust. Many clinics offer loyalty programs or seasonal promotions that can help you save money without sacrificing the quality of the care you receive. By following the checklist and asking the right questions, you can navigate the complex world of aesthetic pricing and achieve the look you want with the peace of mind that you are in safe hands. Focus on the value of the expertise and the safety of the environment rather than just the number at the bottom of the receipt. This approach ensures that your investment in your appearance is both effective and secure.

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